Supramolecular assemblies based on amphiphilic cyclodextrins

The capacity of two types of amphiphilic beta-cyclodextrin (CD) derivatives, heptakis-C6-alkylamido beta-CD (I) and heptakis-C6-ammonium tetradecakis-O2,O3-alkyl beta-CD (II), to form organized assemblies with L-alpha-phosphatidylcholine-dipalmitoyl (dppc) and iota-carrageenan is described. These systems are studied using a Langmuir balance. The formation of stable mixed layers between I and II and dppc is observed. The interaction between II and iota-carrageenan leads to a dimunition in the fluidity of monomolecular layers. The physicochemical properties of I are described via variable temperature H-1-NMR studies.