INCIDENCE OF CHILDHOOD MALIGNANCIES IN THE VICINITY OF WEST-GERMAN NUCLEAR-POWER-PLANTS

被引：62
作者：
MICHAELIS, J
KELLER, B
HAAF, G
KAATSCH, P
机构：
[1] Institut für Medizinische Statistik und Dokumentation, Mainz, D-6500
来源：
CANCER CAUSES & CONTROL | 1992年 / 3卷 / 03期
关键词：
CANCER REGISTRY; CHILDHOOD CANCER; EPIDEMIOLOGY; GERMANY; LEUKEMIA; NUCLEAR INSTALLATIONS; NUCLEAR POWER PLANTS; RISK ASSESSMENT;
D O I：
10.1007/BF00124259
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The incidence of childhood malignancies in 20 areas surrounding major nuclear installations is compared with the incidence in matched control regions. The study is based on the registry of childhood malignancies in the Federal Republic of Germany and includes 1,610 cases which were diagnosed before 15 years of age from 1980 to 1990. The relative risk (RR) was 0.97 for all malignancies and 1.06 for acute leukemia in all regions within a 15 km radius of an installation. Increased RR was observed in subgroups for acute leukemia before five years of age and for lymphomas, especially in regions close to installations (< 5 km) which started operation before 1970. Most of this increase was attributable to an unexpectedly low incidence in the control regions which could not be explained by analyzing possible confounding factors. Using the same control regions, a comparable and even more pronounced increase of RRs was observed in regions where nuclear power plants have been projected.
引用
收藏
页码：255 / 263
页数：9
相关论文
共 19 条
  • [1] Gardner M.J., Winder P.D., Cancer in Cumberland during 1959–68 with reference to cancer in young people around Windscale, Lancet, 1, pp. 216-7, (1984)
  • [2] Baron J.A., Cancer mortality in small areas around nuclear facilities in England and Wales, Br J Cancer, 50, pp. 815-24, (1984)
  • [3] Heasman M.A., Kemp I.W., Urquhart J.D., Black R., Childhood leukemia in northern Scotland, Lancet, 1, (1986)
  • [4] Cook-Mozaffari P.J., Ashwood F.L., Vincent T., Forman D., Alderson M., Cancer Incidence and Mortality in the Vicinity of Nuclear Installations. England and Wales 1950–1980, (1987)
  • [5] Forman D., Cook-Mozaffari P., Darby S., Et al., Cancer near nuclear installations, Nature, 329, pp. 499-505, (1987)
  • [6] Barton C.J., Roman E., Ryder H.M., Watson A., Childhood leukaemia in West Berkshire, Lancet, 2, pp. 1248-9, (1985)
  • [7] Hill C., Laplanche A., Overall mortality and cancer mortality around French nuclear sites, Nature, 347, pp. 755-7, (1990)
  • [8] Viel J.F., Richardson S.T., Childhood leukaemia around the La Hague nuclear waste reprocessing plant, Br Med J, 300, pp. 580-1, (1990)
  • [9] Crump K.S., Ng T.H., Cuddihy R.G., Cancer incidence patterns in the Denver metropolitan area in relation to the Rocky Flats plant, Am J Epid, 126, pp. 127-35, (1987)
  • [10] Hatch M.C., Beyea J., Nieves J.W., Susser M., Cancer near the Three Mile Island nuclear plant: radiation emissions, Am J Epid, 132, pp. 397-417, (1990)
12