COMPLEMENT AND CONTRAST MATERIAL REACTORS

被引：62

作者：

LASSER, EC

LANG, JH

LYON, SG

HAMBLIN, AE

机构：

[1] University of California, San Diego, School of Medicine, Department of Radiology San Diego, CA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 1979年 / 64卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0091-6749(79)90043-5

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Patients showing systemic reactions to intravascular contrast media and patients receiving contrast media without reaction have significantly different mean values (p < 0.05) for functionally determined serum Cl̄-esterase inhibitor (Cl̄ INH) and total hemolytic complement (CH50). The lower concentration of these components in reactors appears in baseline serum samples (as well as after injection), and suggests that many anaphylactoid reactions to contrast media are conditioned by earlier complement consumption, and result directly from contrast-induced activation of complement, and other activation system components in the presence of inhibitor depression. © 1979.

引用

页码：105 / 112

页数：8

共 44 条

[1]

ASGHAR SS, 1976, CLIN EXP IMMUNOL, V25, P244

[2]

AUSMAN J I, 1964, J Surg Res, V4, P349, DOI 10.1016/S0022-4804(64)80082-2

[3] ANTIBODIES TO RADIOGRAPHIC CONTRAST AGENTS - INDUCTION AND CHARACTERIZATION OF RABBIT ANTIBODY [J].