THE BETA-SUBUNIT OF THE GASTRIC H+/K+-ATPASE CAN OCCUR WITHOUT THE ALPHA-SUBUNIT

被引：12

作者：

BALDWIN, GS

机构：

[1] Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, PO Royal Melbourne Hospital

来源：

FEBS LETTERS | 1990年 / 272卷 / 1-2期

关键词：

ATPase; Proton pump;

D O I：

10.1016/0014-5793(90)80473-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The renal Na+/K+-ATPase and the gastric H+/K+-ATPase both contain α- and β-subunits. We report here the identification and partial purification of a second population of the β-subunit of the gastric H+/K+-ATPase, which has no accompanying a-subunit detectable by Coomassie blue staining or by Western blotting with monoclonal antibodies specific for the α-subunit. © 1990.

引用

收藏

页码：159 / 162

页数：4

相关论文

共 20 条

[1]

Baldwin G S, 1987, Protein Seq Data Anal, V1, P7

[2]

BALDWIN GS, 1986, J BIOL CHEM, V261, P2252

[3] ISOLATION OF TRANSFERRIN FROM PORCINE GASTRIC-MUCOSA - COMPARISON WITH PORCINE SERUM TRANSFERRIN [J].

BALDWIN, GS ;

BACIC, T ;

CHANDLER, R ;

GREGO, B ;

PEDERSEN, J ;

SIMPSON, RJ ;

TOH, BH ;

WEINSTOCK, J .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1990, 95 (02) :261-268

[4] PARIETAL-CELL ANTIBODIES IN PERNICIOUS-ANEMIA INHIBIT H+,K+-ADENOSINE TRIPHOSPHATASE, THE PROTON PUMP OF THE STOMACH [J].

BURMAN, P ;

MARDH, S ;

NORBERG, L ;

KARLSSON, FA .

GASTROENTEROLOGY, 1989, 96 (06) :1434-1438

[5] MECHANISTIC ASPECTS OF GASTRIC [H++K+]-ATPASE [J].

FALLER, L ;

JACKSON, R ;

MALINOWSKA, D ;

MUKIDJAM, E ;

RABON, E ;

SACCOMANI, G ;

SACHS, G ;

SMOLKA, A .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1982, 402 (DEC) :146-163

[6]

GOLDKORN I, 1989, J BIOL CHEM, V264, P18768

[7] LOCATION OF THE CARBOHYDRATES PRESENT IN THE HK-ATPASE VESICLES ISOLATED FROM HOG GASTRIC-MUCOSA [J].

HALL, K ;

PEREZ, G ;

ANDERSON, D ;

GUTIERREZ, C ;

MUNSON, K ;

HERSEY, SJ ;

KAPLAN, JH ;

SACHS, G .

BIOCHEMISTRY, 1990, 29 (03) :701-706

[8]

HOROWITZ B, 1990, J BIOL CHEM, V265, P4189

[9] MAJOR PARIETAL-CELL ANTIGEN IN AUTOIMMUNE GASTRITIS WITH PERNICIOUS-ANEMIA IS THE ACID-PRODUCING H+,K+-ADENOSINE TRIPHOSPHATASE OF THE STOMACH [J].

KARLSSON, FA ;

BURMAN, P ;

LOOF, L ;

MARDH, S .

JOURNAL OF CLINICAL INVESTIGATION, 1988, 81 (02) :475-479

[10] RAPID AND SENSITIVE COLORIMETRIC METHOD FOR VISUALIZING BIOTIN-LABELED DNA PROBES HYBRIDIZED TO DNA OR RNA IMMOBILIZED ON NITROCELLULOSE - BIO-BLOTS [J].

LEARY, JJ ;

BRIGATI, DJ ;

WARD, DC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (13) :4045-4049