NMR-STUDIES OF DRUG-METABOLISM AND DISPOSITION

被引：7
|
作者：
BELL, JD
GADIAN, DG
PREECE, NE
机构：
[1] ROYAL COLL SURG ENGLAND,HUNTERIAN INST,DEPT PHYS SURG,35-43 LINCOLNS INN FIELDS,LONDON WC2A 3PN,ENGLAND
[2] HAMMERSMITH HOSP,NUCL MAGNET RESONANCE UNIT,LONDON W12 0HS,ENGLAND
来源：
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS | 1990年 / 15卷 / 02期
关键词：
drug disposition; drug metabolism; In vivo NMR;
D O I：
10.1007/BF03190195
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The ways in which NMR is being used in vivo to study drug metabolism and disposition are reviewed. We also assess the role of this technique as a non - invasive method for monitoring the fate of drugs in human and animals, and for providing information about pharmacology and toxicity. © 1990 Springer-Verlag.
引用
收藏
页码：127 / 133
页数：7
相关论文
共 50 条
  • [41] CONTINUING STUDIES ON EFFECT OF EXPERIMENTAL DIABETES ON DRUG-METABOLISM
    ACKERMAN, DM
    FEDERATION PROCEEDINGS, 1976, 35 (03) : 407 - 407
  • [42] USE OF ANTIFOAMS IN DRUG-METABOLISM STUDIES IN-VITRO
    FRANKLIN, MR
    BIOCHEMICAL PHARMACOLOGY, 1972, 21 (20) : 2697 - &
  • [43] DEUTERIUM-ISOTOPE EFFECTS IN STUDIES OF DRUG-METABOLISM
    FOSTER, AB
    TRENDS IN PHARMACOLOGICAL SCIENCES, 1984, 5 (12) : 524 - 527
  • [44] USE OF HUMAN HEPATOCYTE CULTURES FOR DRUG-METABOLISM STUDIES
    GUILLOUZO, A
    MOREL, F
    FARDEL, O
    MEUNIER, B
    TOXICOLOGY, 1993, 82 (1-3) : 209 - 219
  • [45] NOVEL DRUG-METABOLISM AND EXCRETION STUDIES USING HIGH-RESOLUTION PROTON NMR-SPECTROSCOPY
    NICHOLSON, JK
    TULIP, K
    TIMBRELL, JA
    BALES, JR
    SADLER, PJ
    BRITISH JOURNAL OF CANCER, 1985, 52 (03) : 457 - 457
  • [46] Computational studies on drug-drug interactions and drug-metabolism enzyme interactions
    Ma, Hong
    Fu, Ting
    Li, Guohui
    DRUG METABOLISM REVIEWS, 2011, 43 : 62 - 63
  • [47] USE OF SALMONELLA MUTAGENICITY TEST IN DRUG-METABOLISM STUDIES
    DYBING, E
    AUNE, T
    SODERLUND, EJ
    ACTA PHARMACOLOGICA ET TOXICOLOGICA, 1977, 41 : 31 - 31
  • [48] CONTINUOUS FLOW-FAB IN DRUG-METABOLISM STUDIES
    THENOT, JP
    PADOVANI, P
    VAJTA, S
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1990, 199 : 132 - ANYL
  • [49] DRUG-METABOLISM IN RUMEN
    SCHMID, A
    LOSERTH, J
    REVUE DE MEDECINE VETERINAIRE, 1989, 140 (8-9) : 713 - 717
  • [50] DRUG-METABOLISM BY PLACENTA
    JUCHAU, MR
    PEDERSEN, MG
    FANTEL, AG
    SHEPARD, TH
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 1973, 14 (04) : 673 - 679
12345