SCHIFF-BASES OF N-HYDROXY-N'-AMINOGUANIDINES AS ANTIVIRAL, ANTIBACTERIAL AND ANTICANCER AGENTS

被引：65
作者：
PIGNATELLO, R
PANICO, A
MAZZONE, P
PINIZZOTTO, MR
GAROZZO, A
FURNERI, PM
机构：
[1] IST SCI BIOCHIM & FARMACOL,I-95125 CATANIA,ITALY
[2] IST MICROBIOL,I-95124 CATANIA,ITALY
来源：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 1994年 / 29卷 / 10期
关键词：
N-HYDROXY-N'-AMINOGUANIDINE; ANTIVIRAL ACTIVITY; ANTITUMORAL ACTIVITY;
D O I：
10.1016/0223-5234(94)90137-6
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of Schiff bases of N-hydroxy-N-aminoguanidine tosylate (SB-HAG) were prepared and tested for their in vitro antitumoral, antiviral and antibacterial activities. Several compounds displayed a weak anticancer activity and an interesting activity against viruses.
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页码：781 / 785
页数：5
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