Comparison of Frequency of Healing in patients with Acute Anal Fissure Undergoing Lateral Internal Sphincterotomy Versus Medical Management with GTN 0.2% Cream

Aim: To compare the frequency of healing in patients with acute anal fissure undergoing lateral internal sphincterotomy versus medical management with GTN 0.2% cream. Methods: This randomized controlled trial was conducted at Department of Surgery Nishter Hospital Multan from July 2015 to January 2016. Total 94 patients with acute anal fissure either male or female having age from 20-60 years were included in this study. Results: Total 94 patients with acute anal fissure were included in this study. Mean age of the patients was 39.74 +/- 11.74 years, mean age of the patients of Group A was 39.40 +/- 11.64 years and mean age of the patients of Group B was 40.09 +/- 11.95 years. Healing was noted in 41(87.23%) of Group A and 29(61.67%) patients of Group B. Difference between the frequency of healing of Group A and B was statistically significant (0.008). Conclusion: Results of this study revealed that frequency of healing in patients with acute anal fissure is better in patients managed with Lateral internal sphincterotomy as compare to patients managed the GTN cream. In male patients there is no statistical difference between healing rate of both groups but female patients found with higher healing rate in Lateral internal sphincterotomy group as compare to GTN cream group.