DERIVATIVES OF 3,4-DIHYDROCARBOSTYRIL AS BETA-ADRENERGIC BLOCKING-AGENTS

被引：85
作者：
NAKAGAWA, K [1 ]
MURAKAMI, N [1 ]
YOSHIZAK.S [1 ]
TOMINAGA, M [1 ]
MORI, H [1 ]
YABUUCHI, Y [1 ]
SHINTANI, S [1 ]
机构：
[1] OTSUKA PHARM CO LTD, TOKUSHIMA FACTORY, RES LAB 1, 463-10 KAGASUNO, KAWAUCHI, TOKUSHIMA, JAPAN
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1974年 / 17卷 / 05期
关键词：
D O I：
10.1021/jm00251a013
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The compounds were prepared and their adrenergic .beta.-receptor blocking activity was evaluated by inhibition of the depressor and the positive chronotropic responses to isoproterenol in the dog.
引用
收藏
页码：529 / 533
页数：5
相关论文
共 50 条
  • [41] OXIME ETHER DERIVATIVES OF THIOCHROMAN-4-ONES AS BETA-ADRENERGIC BLOCKING-AGENTS
    FRAVOLINI, A
    SCHIAFFELLA, F
    ORZALESI, G
    SELLERI, R
    VOLPATO, I
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1978, 13 (04) : 347 - 350
  • [42] ANTAGONIZING ACTIVITY OF BETA-ADRENERGIC BLOCKING-AGENTS TO OUABAIN TOXICITY
    SEKIYA, A
    YAMAMOTO, J
    MAEKAWA, H
    [J]. FOLIA PHARMACOLOGICA JAPONICA, 1975, 71 (01) : P8 - P9
  • [43] TREATMENT OF OCULAR HYPERTENSION WITH ORAL BETA-ADRENERGIC BLOCKING-AGENTS
    PANDOLFI, M
    OHRSTROM, A
    [J]. ACTA OPHTHALMOLOGICA, 1974, 52 (04): : 464 - 467
  • [44] EFFECT OF BETA-ADRENERGIC BLOCKING-AGENTS TRIMEPRANOL AND PROPRANOLOL ON ERYTHROPOIESIS
    ZIVNY, J
    OSTADAL, B
    NEUWIRT, J
    [J]. PHYSIOLOGIA BOHEMOSLOVACA, 1980, 29 (05): : 479 - 480
  • [45] BETA-ADRENERGIC BLOCKING-AGENTS IN PATIENTS WITH RENAL-FAILURE
    WARREN, DJ
    SWAINSON, CP
    WRIGHT, N
    [J]. BRITISH MEDICAL JOURNAL, 1974, 3 (5932) : 685 - 685
  • [46] INTRAMOLECULAR HYDROGEN-BONDING IN BETA-ADRENERGIC BLOCKING-AGENTS
    LAXER, M
    CAPOMACCHIA, AC
    HARDEE, GE
    [J]. TALANTA, 1981, 28 (12) : 973 - 976
  • [47] EFFECT OF BETA-ADRENERGIC BLOCKING-AGENTS ON SPONTANEOUS MOTILITY OF MICE
    FABIAN, HEM
    IZQUIERD.JA
    [J]. ARZNEIMITTEL-FORSCHUNG, 1972, 22 (08): : 1375 - &
  • [48] BETA-ADRENERGIC BLOCKING-AGENTS IN THE TREATMENT OF ESSENTIAL-HYPERTENSION
    MINUTILLO, S
    LUPINC, V
    DAGNOLO, B
    [J]. MINERVA MEDICA, 1979, 70 (57) : 3919 - 3924
  • [49] BETA-ADRENERGIC BLOCKING-AGENTS FOR ANTIPSYCHOTIC-INDUCED AKATHISIA
    DOLE, E
    WELLS, BG
    [J]. DRUG INTELLIGENCE & CLINICAL PHARMACY, 1987, 21 (7-8): : 618 - 619
  • [50] BETA-ADRENERGIC BLOCKING-AGENTS TO CONTROL HYPERTENSION IN AVIATION PERSONNEL
    SCHAMROTH, CL
    DAVIDOFF, R
    SCHAMROTH, JM
    MYBURGH, DP
    [J]. AVIATION SPACE AND ENVIRONMENTAL MEDICINE, 1982, 53 (04): : 403 - 404
12345