DERIVATIVES OF 3,4-DIHYDROCARBOSTYRIL AS BETA-ADRENERGIC BLOCKING-AGENTS

被引:85
|
作者
NAKAGAWA, K [1 ]
MURAKAMI, N [1 ]
YOSHIZAK.S [1 ]
TOMINAGA, M [1 ]
MORI, H [1 ]
YABUUCHI, Y [1 ]
SHINTANI, S [1 ]
机构
[1] OTSUKA PHARM CO LTD, TOKUSHIMA FACTORY, RES LAB 1, 463-10 KAGASUNO, KAWAUCHI, TOKUSHIMA, JAPAN
关键词
D O I
10.1021/jm00251a013
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The compounds were prepared and their adrenergic .beta.-receptor blocking activity was evaluated by inhibition of the depressor and the positive chronotropic responses to isoproterenol in the dog.
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收藏
页码:529 / 533
页数:5
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