ALUMINUM DETERMINATION IN THE SKIN OF PATIENTS WITH AND WITHOUT END-STAGE RENAL-FAILURE

被引：2
|
作者：
SUBRA, JF [1 ]
KRARI, N [1 ]
TIROT, P [1 ]
MAURAS, Y [1 ]
BALIT, G [1 ]
VANWEYDEVELT, FC [1 ]
ALLAIN, P [1 ]
机构：
[1] CTR HOSP REG & UNIV ANGERS, PHARMACOL LAB, F-49033 ANGERS, FRANCE
来源：
NEPHRON | 1991年 / 58卷 / 02期
关键词：
ALUMINUM; SKIN; SERUM; DEFEROXAMINE INFUSION TEST; HEMODIALYSIS; RENAL FAILURE;
D O I：
10.1159/000186409
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Aluminium (Al) concentration in the skin was determined by inductively coupled plasma optical emission spectrometry to look for a correlation between Al exposure and skin content in patients with end-stage renal failure. Skin Al concentrations were higher in dialyzed patients than in the nondialyzed group (1.02 +/- 0.30 vs. 0.26 +/- 0.10-mu-g/g; p < 0.001). Moreover, in the dialyzed group, the patients treated for more than 100 months had a higher concentration of Al in the skin than the others (1.20 +/- 0.26 vs. 0.80 +/- 0.18-mu-g/g; p < 0.05). Al skin content correlated better with the deferoxamine infusion test (DIT) than with Al blood plasma concentration. In conclusion, our data confirm that the DIT is a valuable tool for the evaluation of body Al content.
引用
收藏
页码：170 / 173
页数：4
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