ALUMINUM DETERMINATION IN THE SKIN OF PATIENTS WITH AND WITHOUT END-STAGE RENAL-FAILURE

被引：2

作者：

SUBRA, JF ^{[1
]}

KRARI, N ^{[1
]}

TIROT, P ^{[1
]}

MAURAS, Y ^{[1
]}

BALIT, G ^{[1
]}

VANWEYDEVELT, FC ^{[1
]}

ALLAIN, P ^{[1
]}

机构：

[1] CTR HOSP REG & UNIV ANGERS, PHARMACOL LAB, F-49033 ANGERS, FRANCE

来源：

NEPHRON | 1991年 / 58卷 / 02期

关键词：

ALUMINUM; SKIN; SERUM; DEFEROXAMINE INFUSION TEST; HEMODIALYSIS; RENAL FAILURE;

D O I：

10.1159/000186409

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Aluminium (Al) concentration in the skin was determined by inductively coupled plasma optical emission spectrometry to look for a correlation between Al exposure and skin content in patients with end-stage renal failure. Skin Al concentrations were higher in dialyzed patients than in the nondialyzed group (1.02 +/- 0.30 vs. 0.26 +/- 0.10-mu-g/g; p < 0.001). Moreover, in the dialyzed group, the patients treated for more than 100 months had a higher concentration of Al in the skin than the others (1.20 +/- 0.26 vs. 0.80 +/- 0.18-mu-g/g; p < 0.05). Al skin content correlated better with the deferoxamine infusion test (DIT) than with Al blood plasma concentration. In conclusion, our data confirm that the DIT is a valuable tool for the evaluation of body Al content.

引用

页码：170 / 173

页数：4

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