MEASLES, MUMPS, AND RUBELLA ANTIBODIES IN CHILDREN 5-6 YEARS AFTER IMMUNIZATION - EFFECT OF VACCINE TYPE AND AGE AT VACCINATION

被引：58

作者：

BOULIANNE, N

DESERRES, G

RATNAM, S

WARD, BJ

JOLY, JR

DUVAL, B

机构：

[1] LEONARD A MILLER CTR HLTH SERV,NEWFOUNDLAND PUBL HLTH LAB,ST JOHNS,NF A1B 3T2,CANADA

[2] MCGILL UNIV,MONTREAL GEN HOSP,CTR STUDY HOST RESISTANCE,MONTREAL,PQ H3G 1A4,CANADA

[3] UNIV LAVAL,RECH EPIDEMIOL GRP,QUEBEC CITY,PQ G1S 4L8,CANADA

[4] UNIV LAVAL,HOP ST SACREMENT,DEPT SOCIAL & PREVENT MED,QUEBEC CITY,PQ G1S 4L8,CANADA

来源：

VACCINE | 1995年 / 13卷 / 16期

关键词：

MEASLES; MUMPS; RUBELLA; ANTIBODY PREVALENCE; VACCINE; SEROLOGY;

D O I：

10.1016/0264-410X(95)00098-L

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The levels of antibody against measles, mumps, and rubella were determined at 5-6 years postimmunization in 468 children vaccinated with two different trivalent vaccines. The proportions of children without detectable antibody levels were 12 and 3.6% for measles (p<0.001), 14.9 and 7% for mumps (p=0.006), and 3.3 and 3.1% for rubella (p=0.88), respectively, in MMR(R) II and Trivirix(R) recipients. A higher proportion of those vaccinated at younger ages had undetectable or low levels of measles antibody. These data indicate that a large proportion of children vaccinated under routine conditions do not have detectable measles and mumps antibody.

引用

页码：1611 / 1616

页数：6

共 27 条

[1] PERSISTENCE OF MATERNAL ANTIBODY IN INFANTS BEYOND 12 MONTHS - MECHANISM OF MEASLES-VACCINE FAILURE [J].