THE P53-ASSOCIATED PROTEIN MDM2 CONTAINS A NEWLY CHARACTERIZED ZINC-BINDING DOMAIN CALLED THE RING FINGER

被引：81
作者：
BODDY, MN
FREEMONT, PS
BORDEN, KLB
机构：
[1] Protein Structure Laboratory, Imperial Cancer Research Fund, London, WC2A 3PX
[2] Laboratory of Molecular Structure, National Institute for Medical Research, The Ridgeway, London, NW7 1AA, Mill Hill
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1994年 / 19卷 / 05期
关键词：
D O I：
10.1016/0968-0004(94)90020-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：198 / 199
页数：2
相关论文
共 20 条
[1]   FLEXIBLE PROTEIN-SEQUENCE PATTERNS - A SENSITIVE METHOD TO DETECT WEAK STRUCTURAL SIMILARITIES [J].
BARTON, GJ ;
STERNBERG, MJE .
JOURNAL OF MOLECULAR BIOLOGY, 1990, 212 (02) :389-402
[2]   MAPPING OF THE P53 AND MDM-2 INTERACTION DOMAINS [J].
CHEN, JD ;
MARECHAL, V ;
LEVINE, AJ .
MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (07) :4107-4114
[3]  
COLLINS JF, 1988, COMPUT APPL BIOSCI, V4, P67
[4]   AN APOPTOSIS-INHIBITING BACULOVIRUS GENE WITH A ZINC FINGER-LIKE MOTIF [J].
CROOK, NE ;
CLEM, RJ ;
MILLER, LK .
JOURNAL OF VIROLOGY, 1993, 67 (04) :2168-2174
[5]   WILD-TYPE P53 CAN INHIBIT ONCOGENE-MEDIATED FOCUS FORMATION [J].
ELIYAHU, D ;
MICHALOVITZ, D ;
ELIYAHU, S ;
PINHASIKIMHI, O ;
OREN, M .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (22) :8763-8767
[6]   A NOVEL ARRANGEMENT OF ZINC-BINDING RESIDUES AND SECONDARY STRUCTURE IN THE C3HC4 MOTIF ON AN ALPHA HERPES-VIRUS PROTEIN FAMILY [J].
EVERETT, RD ;
BARLOW, P ;
MILNER, A ;
LUISI, B ;
ORR, A ;
HOPE, G ;
LYON, D .
JOURNAL OF MOLECULAR BIOLOGY, 1993, 234 (04) :1038-1047
[7]   TUMORIGENIC POTENTIAL ASSOCIATED WITH ENHANCED EXPRESSION OF A GENE THAT IS AMPLIFIED IN A MOUSE-TUMOR CELL-LINE [J].
FAKHARZADEH, SS ;
TRUSKO, SP ;
GEORGE, DL .
EMBO JOURNAL, 1991, 10 (06) :1565-1569
[8]   THE P53 PROTO-ONCOGENE CAN ACT AS A SUPPRESSOR OF TRANSFORMATION [J].
FINLAY, CA ;
HINDS, PW ;
LEVINE, AJ .
CELL, 1989, 57 (07) :1083-1093
[9]   THE RING FINGER - A NOVEL PROTEIN-SEQUENCE MOTIF RELATED TO THE ZINC-FINGER [J].
FREEMONT, PS .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES-SERIES, 1993, 684 :174-192
[10]   A NOVEL CYSTEINE-RICH SEQUENCE MOTIF [J].
FREEMONT, PS ;
HANSON, IM ;
TROWSDALE, J .
CELL, 1991, 64 (03) :483-484
12