GATING AND CONDUCTANCE PROPERTIES OF A HUMAN DELAYED RECTIFIER K+ CHANNEL EXPRESSED IN FROG OOCYTES

被引：0
|
作者：
BENNDORF, K [1 ]
KOOPMANN, R [1 ]
LORRA, C [1 ]
PONGS, O [1 ]
机构：
[1] UNIV HAMBURG,KRANKENHAUS EPPENDORF,INST NEURONALE SIGNALVERARBEITUNG,ZENTRUM MOLEK NEUROBIOL,D-20251 HAMBURG,GERMANY
来源：
JOURNAL OF PHYSIOLOGY-LONDON | 1994年 / 477卷 / 01期
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D O I：
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中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
1. The human delayed rectifier K+ channel h-DRK1, a homologue to the DRK1 channel in the rat, was expressed in Xenopus oocytes. Single-channel currents were measured in micropatches; macroscopic currents were measured either in macropatches, giant patches, or whole oocytes. 2. Macroscopic currents activated at -20 mV and more positive. The instantaneous current-voltage relationship rectified outwardly to a higher degree than predicted by the Goldman-Hodgkin-Katz equation.
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页码：1 / 14
页数：14
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