MEASUREMENT OF COLONIC TRANSIT-TIME USING RADIONUCLIDE IMAGING - ANALYSIS BY CONDENSED IMAGES

被引：19

作者：

NOTGHI, A

KUMAR, D

PANAGAMUWA, B

TULLEY, NJ

HESSLEWOOD, SR

HARDING, LK

机构：

[1] Physics and Nuclear Medicine, Dudley Road Hospital, Birmingham

[2] Department of Surgery, Queen Elizabeth Hospital, Birmingham

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1993年 / 14卷 / 03期

关键词：

D O I：

10.1097/00006231-199303000-00010

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A polymer-coated capsule has been used in eight volunteer subjects to deliver In-111-resin into the ileocaecal region. The images were acquired for up to 3 days to follow transit through the colon. Expressing the results of individual studies is difficult and time-activity curves for each region are confusing. Calculation of the geometric centre indicates only where the middle of the activity has reached. We describe a new method of presenting colonic transit data as parametric images. The parametric images show the amount of activity in each area of interest as the study progresses. This is readily understood and allows segmental movement of the isotope, either forward or retrograde, to be examined. The geometric mean of activity in four areas of the colon were also calculated. Four hours after reaching the ileocaecal region, 65% (S.D. 24%) of the activity was in the caecum and 26% (S.D. 20%) in the transverse colon. By 24 h three controls had excreted most of the activity, in two the activity was mainly in the rectum and in two there was still some activity in the transverse colon. A protocol for colonic transit studies, problems with analysis and a new method of presentation of data are discussed.

引用

页码：204 / 211

页数：8

共 14 条

[1]

Chaudhary N.A., Truelove S.C., Colonic motility - a critical review of methods and results, Am J. Med, 31, pp. 86-106, (1961)

[2]

Schindlbeck N.E., Klauser A.G., Muller-Lissner S.A., Measurement of colon transit time (German), Z Gastroenterol, 28, pp. 399-404, (1990)

[3]

Couturier D., Chaussade S., Total and segmental colonic transit times. Measurements by radio-opaque markers (French), Presse Med, 17, pp. 69-73, (1988)

[4]

Kruis W., Phillips S., Zinsmeister A., Flow across the canine ileocolonic junction: Role of the ileocolonic sphincter, Am J Physiol, 252, pp. G13-G18, (1987)

[5]

Softer E.E., Scalabrini P., Wingate D.L., Prolonged ambulant monitoring of human colonic motility, Am J Physiol, 257, (1989)

[6]

Dapoigny M., Sarna S.K., Effects of physical exercise on colonic motor activity, Am J. Physiol, 260, (1991)

[7]

Cook I.J., Reddy S.N., Collins S.M., Daniel E.E., Influence of recording techniques on measurement of canine colonic motility, Dig Dis Sci, 33, pp. 999-1006, (1988)

[8]

Shields R.A., Lawson R.S., Effective dose equivalent (Editorial), Nucl Med Commun, 8, pp. 851-855, (1987)

[9]

Stivland T., Camilleri M., Vassallo M., Proano M., Rath D., Brown M., Thomforde G., Pemberton J., Phillips S., Scintigraphic measurement of regional gut transit in idiopathic constipation, Gastroenterology, 101, pp. 107-115, (1991)

[10]

Camilleri M., Colemont L.J., Phillips S.F., Brown M.L., Thomforde G.M., Chapman N., Zinsmeister A.R., Human gastric emptying and colonic filling of solids characterized by a new method, Am J Physiol, 257, (1989)

← 1 2 →