BILATERAL VIRILIZING SCLEROSING STROMAL TUMORS OF THE OVARY IN A PREGNANT WOMAN WITH GORLINS SYNDROME - IMPLICATIONS FOR PATHOGENESIS OF OVARIAN STROMAL NEOPLASMS

被引：55

作者：

ISMAIL, SM ^{[1
]}

WALKER, SM ^{[1
]}

机构：

[1] UNIV HOSP WALES,DEPT OBSTET & GYNAECOL,CARDIFF CF4 4XW,S GLAM,WALES

来源：

HISTOPATHOLOGY | 1990年 / 17卷 / 02期

关键词：

Gorlin's syndrome; hormone synthesis; ovary; sclerosing; stromal tumour;

D O I：

10.1111/j.1365-2559.1990.tb00688.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A woman with Gorlin's syndrome who had become pregnant following clomiphene therapy presented in early pregnancy with bilateral ovarian sclerosing stromal tumours which were associated with profound virilization. Pre‐ and post‐operative hormone profiles indicated androgen production by the tumours. Ovarian sclerosing stromal tumours have not previously been reported as occurring bilaterally or in association with Gorlin's syndrome. We discuss the questions raised by this unusual case regarding the pathogenesis of ovarian stromal neoplasms. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：159 / 163

页数：5

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