SYNTHESIS OF OPTICALLY PURE ALPHA-ALKYLATED ALPHA-AMINO-ACIDS AND A SINGLE-STEP METHOD FOR ENANTIOMERIC EXCESS DETERMINATION

被引：156
作者：
KRUIZINGA, WH
BOLSTER, J
KELLOGG, RM
KAMPHUIS, J
BOESTEN, WHJ
MEIJER, EM
SCHOEMAKER, HE
机构：
[1] STATE UNIV GRONINGEN,DEPT ORGAN CHEM,NIJENBORGH 16,9747 AG GRONINGEN,NETHERLANDS
[2] DSM RES,BIOORGAN CHEM SECT,GELEEN 6160 MD,NETHERLANDS
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1988年 / 53卷 / 08期
关键词：
D O I：
10.1021/jo00243a049
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
引用
收藏
页码：1826 / 1827
页数：2
相关论文
共 37 条
[1]   ASYMMETRIC-SYNTHESIS OF ALPHA-DISUBSTITUTED AMINO-ACIDS [J].
BAJGROWICZ, JA ;
COSSEC, B ;
PIGIERE, C ;
JACQUIER, R ;
VIALLEFONT, P .
TETRAHEDRON LETTERS, 1983, 24 (35) :3721-3724
[2]  
BAJGROWICZ JA, 1984, TETRAHEDRON LETT, V25, P1789, DOI 10.1016/S0040-4039(01)90042-5
[3]  
BARRETT GC, 1979, AMINO ACIDS PEPT PRO, V10, P11
[4]  
BENOITON NL, 1979, INT J PEPT PROT RES, V13, P403
[5]  
BOESTEN WHJ, 1984, Patent No. 150854
[6]   RESOLUTION OF DL-ALPHA-METHYLPHENYLALANINE [J].
BOLLINGER, FW .
JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (04) :373-+
[7]  
BREUER W, 1982, J CHEM RES-S, P271
[8]   NUCLEAR MAGNETIC-RESONANCE SPECTRA OF BENZOYLDIPEPTIDE ESTERS - CONVENIENT TEST FOR RACEMIZATION IN PEPTIDE-SYNTHESIS [J].
DAVIES, JS ;
THOMAS, RJ ;
WILLIAMS, MK .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1975, (03) :76-77
[9]   ALPHA-ALKYLATION OF ACYCLIC AMINO-ACIDS WITH SELF-REPRODUCTION OF THE CENTER OF CHIRALITY - A NEW ROUTE TO (S)-(+)-ALPHA-ALKYLATED ASPARTIC ACIDS [J].
FADEL, A ;
SALAUN, J .
TETRAHEDRON LETTERS, 1987, 28 (20) :2243-2246
[10]   ENANTIOMERIC EXCESS DETERMINATION WITHOUT CHIRAL AUXILIARY COMPOUNDS - A NEW P-31 NMR METHOD FOR AMINO-ACID ESTERS AND PRIMARY AMINES [J].
FERINGA, BL ;
STRIJTVEEN, B ;
KELLOGG, RM .
JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (26) :5484-5486
1234