DNA CYTOPHOTOMETRY IN ADRENOCORTICAL TUMORS - A CLINICOMORPHOLOGICAL STUDY OF 66 CASES

被引：21
|
作者：
PADBERG, BC
LAURITZEN, I
ACHILLES, E
HOLL, K
BRESSEL, M
KLOPPEL, G
DRALLE, H
SCHRODER, S
机构：
[1] GEN HOSP HAMBURG,DEPT UROL,HARBURG,GERMANY
[2] HANOVER UNIV MED,DEPT SURG,HANNOVER,GERMANY
[3] FREE UNIV BRUSSELS,INST PATHOL,B-1050 BRUSSELS,BELGIUM
来源：
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1991年 / 419卷 / 03期
关键词：
ADRENOCORTICAL TUMORS; DNA CYTOPHOTOMETRY; DIFFERENTIAL DIAGNOSIS; PROGNOSIS;
D O I：
10.1007/BF01626343
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
Surgical specimens of 66 adrenocortical tumours were investigated by conventional microscopy and DNA cytophotometry. Histologically, 50 neoplasms were classified as adenomas and 16 as carcinomas. In only 8 of the latter cases were distant metastases and/or a lethal outcome recorded. On single cell scanning cytophotometry either non-euploid or aneuploid DNA histograms were identified in 24 of 50 adenomas (48%) and in 14 of 16 carcinomas (88%). The two carcinomas exhibiting euploid DNA distributions fell into the group of 7 malignancies which are recurrence-free so far. From these findings it is concluded that DNA measurements have no diagnostic and only limited prognostic value in neoplasms of the adrenal cortex.
引用
收藏
页码：167 / 170
页数：4
相关论文
共 50 条
  • [1] DNA CYTOPHOTOMETRY AND PROGNOSIS IN OVARIAN-TUMORS OF BORDERLINE MALIGNANCY - A CLINICOMORPHOLOGICAL STUDY OF 80 CASES
    PADBERG, BC
    ARPS, H
    FRANKE, U
    THIEDEMANN, C
    REHPENNING, W
    STEGNER, HE
    LIETZ, H
    SCHRODER, S
    DIETEL, M
    CANCER, 1992, 69 (10) : 2510 - 2514
  • [2] IMMUNOCYTOCHEMISTRY IN ADRENOCORTICAL TUMORS - A CLINICOMORPHOLOGICAL STUDY OF 72 NEOPLASMS
    SCHRODER, S
    PADBERG, BC
    ACHILLES, E
    HOLL, K
    DRALLE, H
    KLOPPEL, G
    VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1992, 420 (01) : 65 - 70
  • [3] Oncocytic adrenocortical tumors: Study of four cases
    Minaidou, E.
    Dimitriadi, A.
    Souka, E.
    Kyrodimou, E.
    Choreftaki, T.
    Papaliodi, E.
    VIRCHOWS ARCHIV, 2013, 463 (02) : 160 - 160
  • [4] ADRENOCORTICAL TUMORS IN CHILDREN - STUDY OF 22 CASES
    WEATHERBY, RP
    CARNEY, JA
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1982, 78 (02) : 269 - 269
  • [5] RESULTS OF DNA CYTOPHOTOMETRY ON SECTIONS OF MALIGNANT-TUMORS
    HAROSEK, G
    THEISSIG, F
    DIMMER, V
    KUNZE, KD
    MEYER, W
    ACTA HISTOCHEMICA, 1990, : 139 - 145
  • [6] Tumors of the salivary glands based on a study of 66 cases
    Schreiner, BF
    Mattick, WL
    AMERICAN JOURNAL OF ROENTGENOLOGY AND RADIUM THERAPY, 1929, 21 : 541 - 546
  • [7] Metastatic tumors of the vulva - A clinicopathologic study of 66 cases
    Neto, AG
    Deavers, MT
    Silva, EG
    Malpica, A
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2003, 27 (06) : 799 - 804
  • [8] Oncocytic Adrenocortical Tumors: Diagnostic Algorithm and Mitochondrial DNA Profile in 27 Cases
    Duregon, Eleonora
    Volante, Marco
    Cappia, Susanna
    Cuccurullo, Alessandra
    Bisceglia, Michele
    Wong, Daniel D.
    Spagnolo, Dominic V.
    Szpak-Ulczok, Sylwia
    Bollito, Enrico
    Daffara, Fulvia
    Berruti, Alfredo
    Terzolo, Massimo
    Papotti, Mauro
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2011, 35 (12) : 1882 - 1893
  • [9] Pediatric craniopharyngiomas: Clinicomorphological study of 189 cases
    Zhang, YQ
    Wang, CC
    Ma, ZY
    PEDIATRIC NEUROSURGERY, 2002, 36 (02) : 80 - 84
  • [10] ADRENOCORTICAL TUMORS IN CHILDREN - CONCERNING 10 CASES
    PELLERIN, D
    HAROUCHI, A
    SOULIER, Y
    ANNALES DE CHIRURGIE INFANTILE, 1975, 16 (03): : 155 - 179
12345