CHIRAL SEPARATION OF DINICONAZOLE, UNICONAZOLE AND STRUCTURALLY RELATED-COMPOUNDS BY CYCLODEXTRIN-MODIFIED MICELLAR ELECTROKINETIC CHROMATOGRAPHY

被引：29
|
作者：
FURUTA, R
DOI, T
机构：
[1] Environmental Health Science Laboratory, Sumitomo Chemical Company, Osaka
来源：
ELECTROPHORESIS | 1994年 / 15卷 / 10期
关键词：
D O I：
10.1002/elps.11501501201
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Enantiomeric separation of the structural analogs, diniconazole and uniconazole, can be achieved by cyclodextrin (CD)-modified micellar electrokinetic chromatography (MEKC). The elution behavior of other structurally related compounds was therefore investigated and compared with that in highperformance liquid chromatography (HPLC) using a CD-bonded stationary phase. From the results, it was concluded that the benzene ring of the solute plays an important role in formation of CD complexes and chiral recognition in MEKC as well as in HPLC, although the enantioselectivity with the two methods was different. Nuclear magnetic resonance (NMR) data revealed different CD effects on the solute between the MEKC and HPLC models.
引用
收藏
页码：1322 / 1325
页数：4
相关论文
共 50 条
  • [21] Separation of polycyclic aromatic hydrocarbon metabolites by γ-cyclodextrin-modified micellar electrokinetic chromatography
    Xu, X
    Hurtubise, RJ
    JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2000, 23 (11) : 1657 - 1670
  • [22] Chiral separation of pemoline enantiomers by cyclodextrin-modified micellar capillary chromatography
    Zhu, CF
    Lin, XL
    Wei, YJ
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2002, 30 (02) : 293 - 298
  • [23] Simultaneous separation and determination of hirsutine and hirsuteine by cyclodextrin-modified micellar electrokinetic capillary chromatography
    Wang, Mengli
    Guo, Jing
    Wang, Zhiying
    Zhang, Guangbin
    Yu, Haixia
    Chang, Ruimiao
    Chen, Anjia
    PHYTOCHEMICAL ANALYSIS, 2020, 31 (01) : 112 - 118
  • [24] Enantioseparation of esbiothrin by cyclodextrin-modified microemulsion and micellar electrokinetic chromatography
    Chu, Bao-Lin
    Guo, Bao-Yuan
    Wang, Zhihua
    Lin, Jin-Ming
    JOURNAL OF SEPARATION SCIENCE, 2008, 31 (22) : 3911 - 3920
  • [25] Separation of alkamides from Echinacea purpurea extracts by cyclodextrin-modified micellar electrokinetic chromatography
    Gotti, R
    Fiori, J
    Hudaib, M
    Cavrini, V
    ELECTROPHORESIS, 2002, 23 (17) : 3084 - 3092
  • [26] ENANTIOMERIC SEPARATION BY CYCLODEXTRIN-MODIFIED MICELLAR ELECTROKINETIC CHROMATOGRAPHY USING BILE-SALT
    LIN, M
    WU, NA
    BARKER, GE
    SUN, P
    HUIE, CW
    HARTWICK, RA
    JOURNAL OF LIQUID CHROMATOGRAPHY, 1993, 16 (17): : 3667 - 3674
  • [27] Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography
    Borst, Claudia
    Holzgrabe, Ulrike
    JOURNAL OF CHROMATOGRAPHY A, 2008, 1204 (02) : 191 - 196
  • [28] CHIRAL SEPARATION OF DILTIAZEM, TRIMETOQUINOL AND RELATED-COMPOUNDS BY MICELLAR ELECTROKINETIC CHROMATOGRAPHY WITH BILE-SALTS
    NISHI, H
    FUKUYAMA, T
    MATSUO, M
    TERABE, S
    JOURNAL OF CHROMATOGRAPHY, 1990, 515 : 233 - 243
  • [29] Solid phase extraction/cyclodextrin-modified micellar electrokinetic chromatography for the analysis of melatonin and related indole compounds in plants
    Gomez, Federico J. V.
    Gatica Hernandez, Ismael
    Cerutti, Soledad
    Silva, Maria F.
    MICROCHEMICAL JOURNAL, 2015, 123 : 22 - 27
  • [30] Optimised separation of endogenous urinary components using cyclodextrin-modified micellar electrokinetic capillary chromatography
    Alfazema, LN
    Howells, S
    Perrett, D
    ELECTROPHORESIS, 2000, 21 (12) : 2503 - 2508
12345