POLYMORPHIC VENTRICULAR-TACHYCARDIA WITH CARDIAC SARCOIDOSIS - TREATMENT WITH LOW-DOSE METOPROLOL AND CIBENZOLINE

被引：5

作者：

OKAMOTO, M

HASHIMOTO, M

SUEDA, T

MUNEMORI, M

YAMADA, T

机构：

[1] the Department of Cardiology, Hiroshima Prefectural Hospital, Minami-, ku, Hiroshima, 734

[2] From the Department of Cardiology, Hiroshima Prefectural Hospital, Hiroshima

来源：

INTERNAL MEDICINE | 1994年 / 33卷 / 05期

关键词：

TORSADES-DE-POINTES; BETA-BLOCKERS;

D O I：

10.2169/internalmedicine.33.296

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 38-year-old female had felt exertional dyspnea for six months. Physical examination and laboratory data, including angiotensin-converting enzyme, failed to diagnose sarcoidosis. Her chest X-ray showed cardiomegaly but no hilar lymph node enlargement. Holter ECG showed nonsustained and sustained ventricular tachycardias, monomorphic or polymorphic tachycardia. Echocardiography and contrast left ventriculography showed left ventricular dilatation and generalized hypo- and akinesis. Endomyocardial biopsy revealed myocardial sarcoidosis. Administration of corticosteroids, metoprolol of 20 mg/day and cibenzoline of 300 mg/day was markedly effective for the treatment of ventricular tachycardia. This patient is alive for one year after treatment and the combination therapy seems to contribute to good prognosis.

引用

页码：296 / 299

页数：4

共 10 条

[1]

Bernstein M., Konzelmann F.W., Sidlick D.M., Boeck's sarcoid. A report of a case with visual involvement, Arch Intern Med, 44, (1929)

[2]

Longpore W.T., Freiman D.G., Study of sarcoidosis on combined investigation of 160 cases including 30 autopsies from Johns Hopkins Hospital and Massachusetts General Hospital, Medicine, 31, (1952)

[3]

Stein E., Jackler B., Stimmel W., Sitzbach L., Asymptomatic electrocardiographic alterations in sarcoidosis, Am Heart J, 86, (1973)

[4]

Bashour F.A., Mcconnell T., Skinner W., Hanson M., Myocardial sarcoidosis, Diseases of the Chest, 53, (1968)

[5]

Numao Y., Sekiguchi M., Furuie T., Et al., Evaluation of cardiac involvement through electrocardiogram in patients with sarcoidosis, Kokyu to Junkan, 29, (1981)

[6]

Sekiguchi M., Kaneko M., Hiroe M., Hirosawa K., Recent trends in cardiac sarcoidosis research in Japan, Heart and Vessels, 1, (1985)

[7]

Vaughan-Williams E.M., Classification of antiarrhythmic drugs

[8]

Pharmacology of antiarrhythmic agents, (1981)

[9]

Shiotani H., Miyazaki T., Matsunaga K., Kado T., Improvement of severe heart failure with corticosteroid therapy in a patient with myocardial sarcoidosis, Jpn Circ J, 55, (1991)

[10]

Soffer J., Dreifus L.S., Michelson E.L., Polymorphous ventricular tachycardia associated with normal and long QT intervals, Am J Cardiol, 49, (1982)

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