APPLICATION OF MIXED-MODE, SOLID-PHASE EXTRACTION IN ENVIRONMENTAL AND CLINICAL-CHEMISTRY - COMBINING HYDROGEN-BONDING, CATION-EXCHANGE AND VANDERWAALS INTERACTIONS

被引：37

作者：

MILLS, MS ^{[1
]}

THURMAN, EM ^{[1
]}

PEDERSEN, MJ ^{[1
]}

机构：

[1] CLIN REFERENCE LAB,LENEXA,KS 66214

来源：

JOURNAL OF CHROMATOGRAPHY | 1993年 / 629卷 / 01期

关键词：

D O I：

10.1016/0021-9673(93)80349-D

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Silica- and styrene-divinylbenzene-based mixed-mode resins that contain C-8, C18 and sulphonated cation-exchange groups were compared for their efficiency in isolation of neutral triazine compounds from water and of the basic drug, benzoylecgonine, from urine. The triazine compounds were isolated by a combination of Van der Waals and hydrogen-bonding interactions, and benzoylecgonine was isolated by Van de Waals interactions and cation exchange. All analytes were eluted with a polar organic solvent containing 2% ammonium hydroxide. Larger recoveries (95%) were achieved on copolymerized mixed-mode resins where C18 and sulfonic acid are in closer proximity than on ''blended'' mixed-mode resins (60-70% recovery).

引用

页码：11 / 21

页数：11

共 20 条

[1] EXTRACTION AND ISOLATION OF TRIAZINE HERBICIDES FROM WATER AND VEGETABLES BY A DOUBLE TRAP TANDEM SYSTEM [J].