PREBIOTIC SYNTHESIS OF OROTIC-ACID PARALLEL TO THE BIOSYNTHETIC-PATHWAY

被引：16
作者：
YAMAGATA, Y
SASAKI, K
TAKAOKA, O
SANO, S
INOMATA, K
KANEMITSU, K
INOUE, Y
MATSUMOTO, I
机构：
[1] KANAZAWA UNIV,FAC SCI,DEPT CHEM,KANAZAWA,ISHIKAWA 920,JAPAN
[2] KANAZAWA MED UNIV,MED RES INST,DIV HUMAN GENET & ANTHROPOL,KAHOKU,ISHIKAWA 92002,JAPAN
来源：
ORIGINS OF LIFE AND EVOLUTION OF THE BIOSPHERE | 1990年 / 20卷 / 05期
关键词：
D O I：
10.1007/BF01808133
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
By heating an aqueous solution of aspartic acid and urea, carbamylaspartic acid is first formed and then the molecule is cyclized to dihydroorotic acid (DHO) with loss of water. Irradiation of an aqueous solution of DHO with a tungsten lamp yields orotic acid by photo-dehydrogenation of the molecule. This pathway of orotic acid formation is quite similar to that of biosynthesis of the molecule.
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页码：389 / 399
页数：11
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