PALLADIUM-CATALYZED SYNTHESIS OF TRANS-2,5-DIARYLTETRAHYDROFURANS, POTENT PLATELET-ACTIVATING FACTOR ANTAGONISTS

被引：72
作者：
LAROCK, RC
GONG, WH
机构：
[1] Department of Chemistry, Iowa State University, Ames
来源：
JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 02期
关键词：
D O I：
10.1021/jo00289a002
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
: trans-2,5-Diaryltetrahydrofurans 1–3, potent platelet-activating factor antagonists, have been synthesized regio- and stereoselectively by a three-step approach involving sequential palladium-catalyzed diarylation of 2,3-dihydrofuran and subsequent hydrogenation. © 1990, American Chemical Society. All rights reserved.
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页码：407 / 408
页数：2
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