PALLADIUM-CATALYZED SYNTHESIS OF TRANS-2,5-DIARYLTETRAHYDROFURANS, POTENT PLATELET-ACTIVATING FACTOR ANTAGONISTS

被引：72

作者：

LAROCK, RC

GONG, WH

机构：

[1] Department of Chemistry, Iowa State University, Ames

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 02期

关键词：

D O I：

10.1021/jo00289a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

: trans-2,5-Diaryltetrahydrofurans 1–3, potent platelet-activating factor antagonists, have been synthesized regio- and stereoselectively by a three-step approach involving sequential palladium-catalyzed diarylation of 2,3-dihydrofuran and subsequent hydrogenation. © 1990, American Chemical Society. All rights reserved.

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页码：407 / 408

页数：2

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