THE ORIGIN OF MATRIX METALLOPROTEINASES AND THEIR FAMILIAL RELATIONSHIPS

被引：184

作者：

MURPHY, GJP ^{[1
]}

MURPHY, G ^{[1
]}

REYNOLDS, JJ ^{[1
]}

机构：

[1] STRANGEWAYS RES LAB, DEPT CELL & MOLEC BIOL, CAMBRIDGE CB1 4RN, ENGLAND

来源：

FEBS LETTERS | 1991年 / 289卷 / 01期

关键词：

MATRIX METALLOPROTEINASE; SEQUENCE ALIGNMENT; PHYLOGENY;

D O I：

10.1016/0014-5793(91)80895-A

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

New computer comparisons of the sequences of mammalian matrix metalloproteinases have established for the first time strong links with bacterial metalloproteinases. We also propose that there are five groups in the family of matrix metalloproteinases, although only three are as yet well-characterized as proteins, and discuss their origin and relationships with other zinc containing proteases.

引用

页码：4 / 7

页数：4

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