EXTRACTION OF BACCHARIS CORDIFOLIA PLANT PARTS AND ITS EVALUATION FOR ANTI OXIDANT ACTIVITY

被引：0

作者：

Kumar, Gampa Vijaya ^{[1
]}

Kulkarni, Nagaraju. M. ^{[2
]}

Sruthi, Y. ^{[2
]}

Raju, S.

机构：

[1] KGR Inst Technol & Management, Dept Pharm, Rangareddy, Telangana, India

[2] KGR Inst Technol & Management, Rangareddy, Telangana, India

来源：

INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2016年 / 3卷 / 12期

关键词：

Baccharis cordifolia; anti-oxidant; azathioprine;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The present study is to evaluate the antioxidant activity of Baccharis cordifolia against azathioprine induced oxidative stress in rats Baccharis cordifolia posses considerable pharmacological actions such as antimicrobial, anticancer, anti-inflammator, analgesic, antiarthritic, antibacterial, anti-HIV, and antihelminthic activities. From these results, ideas for future molecular modifications leading to compounds with greater favorable pharmacological properties maybe derived. Baccharis cordifolia has antioxidant activity against Azathioprine induced oxidative stress in rats by decreasing the oxidative stress biomarkers serum creatinine, serum urea in kidneys. high scavenging activity against DPPH free radical generating system. nephropretective effect against Azathioprine induced toxicity in kidneys by observing the histopathological changes in rat kidney tissues. many pharmacological activities like anticancer, antimicrobial, anti-inflammatory, analgesic, antiarthritic, antibacterial, anti-HIV, and antihelmntic activities.

引用

页码：1559 / 1564

页数：6

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