AMBIGUITY OF TRANSLATION - A EUKARYOTIC VERSION

被引:0
作者
INGEVECHTOMOV, SG [1 ]
MIRONOVA, LN [1 ]
TERAVANESYAN, MD [1 ]
机构
[1] RUSSIAN ACAD MED SCI,SCI CTR CARDIOL,MOSCOW 121552,RUSSIA
来源
GENETIKA | 1994年 / 30卷 / 08期
关键词
D O I
暂无
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
In this review, the results of studies on genetic control of translation in the yeasts are considered and analyzed. The studies were performed on the system of the SUP35(SUP2) and SUP45(SUP1) genes. Based on data from genetic analysis, the study of protein synthesis in mutants at these genes, sequencing of both genes, deletion analysis of their functions, and the discovery of homologues of these genes in other eukaryotes, it may be assumed that the gene system under study is a specific evolutionarily conservative system for eukaryotes. This system not only controls translational fidelity, but also ensures integration of translation with other cellular processes.
引用
收藏
页码:1022 / 1035
页数:14
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