REDUCED LIPID CONTAMINATION IN IN-VIVO H-1 MRSI USING TIME-DOMAIN FITTING AND NEURAL-NETWORK CLASSIFICATION

被引:20
作者
DEBEER, R
MICHELS, F
VANORMONDT, D
VANTONGEREN, BPO
LUYTEN, PR
VANVROONHOVEN, H
机构
[1] University of Technology Delft, Department of Applied Physics, 2600 GA Delft
[2] MR Physics Department, Philips Medical Systems, 5680 DA Best
关键词
SPECTROSCOPIC IMAGING; LIPID CONTAMINATION; TIME-DOMAIN FITTING; NEURAL NETWORK CLASSIFICATION;
D O I
10.1016/0730-725X(93)90220-8
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
It is a well-known problem that metabolite maps, reconstructed from in vivo H-1 MRSI data sets, may suffer from contamination caused by the presence of strong lipid signals. In the present investigation, the lipid problem was addressed by applying specific signal processing and data-analysis techniques, combined with pattern recognition based on the concept of the artificial neural network. In order to arrive at images, cleaned from lipid artifacts, we have applied our previously introduced iterative and noniterative time-domain fitting procedures. Furthermore, reduction in computational time of the image reconstructions could be realized by using information provided by a neural network classification of the spectra, calculated from the MRSI data sets.
引用
收藏
页码:1019 / 1026
页数:8
相关论文
共 22 条
[1]  
Luyten, Marien, Van Gerwen, Den Hollander, Localized <sup>1</sup>H NMR spectroscopic imaging of the human brain at 1.5 T, Book of abstracts: Ninth Annual Meeting of the Society of Magnetic Resonance in Medicine, (1990)
[2]  
Luyten, Marien, Den Hollander, Acquisition and quantitation in proton spectroscopy, NMR Biomed., 4, pp. 64-69, (1991)
[3]  
Hu, Patel, Garwood, Ugurbil, Merkle, Grad, Stillman, Reduction of lipid signal contamination in proton chemical shift imaging by Bayesian reconstruction, Book of abstracts: Eleventh Annual Meeting of the Society of Magnetic Resonance in Medicine, (1992)
[4]  
Lloyd, Richie, Raidy, Feng, Neural network classification of MRS using Prony's method, Book of abstracts: Eleventh Annual Meeting of the Society of Magnetic Resonance in Medicine, (1992)
[5]  
Barkhuijsen, De Beer, Van Ormondt, Improved algorithm for noniterative time-domain model fitting to exponentially damped magnetic resonance signals, J. Magn. Reson., 73, pp. 553-557, (1987)
[6]  
De Beer, Van Ormondt, Pijnappel, Improved harmonic retrieval from noisy signals by invoking prior knowledge, Signal Processing IV. Theories and Applications, pp. 1283-1286, (1988)
[7]  
De Beer, Van Ormondt, Analysis of NMR data using time domain fitting procedures, NMR 26. In-Vivo Magnetic Resonance Spectroscopy I: Probeheads and Radiofrequency Pulses, Spectrum Analysis, pp. 202-248, (1992)
[8]  
Meyer, Hansen, Nute, Albersheim, Darvill, York, Sellers, Identification of the <sup>1</sup>H-NMR spectra of complex oligosaccharides with artificial neural networks, Science, 251, pp. 542-544, (1991)
[9]  
Howells, Maxwell, Peet, Griffiths, An investigation of tumour <sup>1</sup>H nuclear magnetic resonance spectra by the application of chemometric techniques, Book of abstracts: Eleventh Annual Meeting of the Society of Magnetic Resonance in Medicine, (1992)
[10]  
Ordidge, Bendall, Gordon, Connelly, Volume selection for in-vivo biological spectroscopy, Magnetic Resonance in Biology and Medicine, pp. 387-397, (1985)