CONCENTRATIONS OF SERUM AMYLOID-A (SAA) AND HAPTOGLOBIN (HP) AS PARAMETERS OF INFLAMMATORY DISEASES IN CATTLE

被引：183

作者：

ALSEMGEEST, SPM ^{[1
]}

KALSBEEK, HC ^{[1
]}

WENSING, T ^{[1
]}

KOEMAN, JP ^{[1
]}

VANEDEREN, AM ^{[1
]}

GRUYS, E ^{[1
]}

机构：

[1] UNIV UTRECHT, FAC VET MED, DEPT LARGE ANIM MED & NUTR, 3508 TD UTRECHT, NETHERLANDS

来源：

VETERINARY QUARTERLY | 1994年 / 16卷 / 01期

关键词：

D O I：

10.1080/01652176.1994.9694410

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The concentrations of the acute-phase proteins, serum amyloid-A (SAA) and haptoglobin (Hp), were determined in the plasma of healthy cows (n=25) and cows with spontaneous acute (n=6), subacute (n=37), or chronic (n=7) inflammatory diseases. The plasma concentration of SAA alone, Hp alone, and the Hp/SAA ratio, differed significantly (p<0.001) between healthy animals and animals with inflammatory diseases. Plasma Hp concentrations in the group of cows with acute inflammatory diseases were significantly (p<0.01) different from those in the group with chronic inflammatory diseases. Moreover, the Hp/SAA ratio in chronic inflammatory diseases was significantly different from this ratio in acute (p<0.01) and subacute (p<0.05) inflammatory diseases. It is therefore concluded that the plasma concentrations of SAA and Hp and the Hp/SAA ratio are useful parameters to distinguish healthy animals from animals with inflammation and can be helpful in distinguishing between acute and chronic of inflammatory diseases.

引用

页码：21 / 23

页数：3

共 24 条

[11] CHARACTERIZATION OF BOVINE AMYLOID PROTEIN-SAA AND PROTEIN-AA
HUSEBEKK, A
HUSBY, G
SLETTEN, K
SKOGEN, B
NORDSTOGA, K
[J]. SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1988, 27 (06) : 739 - 743
[12] KOJ A, 1985, ACUTE PHASE RESPONSE, P161
[13] QUANTITATIVE-DETERMINATION OF BOVINE SERUM HAPTOGLOBIN AND ITS ELEVATION IN SOME INFLAMMATORY DISEASES
MAKIMURA, S
SUZUKI, N
[J]. JAPANESE JOURNAL OF VETERINARY SCIENCE, 1982, 44 (01): : 15 - 21
[14] MAUDSLEY S, 1987, CLIN EXP IMMUNOL, V67, P662
[15] BOVINE HAPTOGLOBIN - SINGLE RADIAL IMMUNODIFFUSION ASSAY OF ITS POLYMERIC FORMS AND DRAMATIC RISE IN ACUTE-PHASE SERA
MORIMATSU, M
SARIKAPUTI, M
SYUTO, B
SAITO, M
YAMAMOTO, S
NAIKI, M
[J]. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 1992, 33 (04) : 365 - 372
[16] MORIMATSU M, 1991, J BIOL CHEM, V266, P11833
[17] OORT J, 1976, INFLAMMATION MECHANI, P25
[18] SERUM AMYLOID A PROTEIN (SAA) IN HORSES - OBJECTIVE MEASUREMENT OF THE ACUTE PHASE RESPONSE
PEPYS, MB
BALTZ, ML
TENNENT, GA
KENT, J
OUSEY, J
ROSSDALE, PD
[J]. EQUINE VETERINARY JOURNAL, 1989, 21 (02) : 106 - 109
[19] ACUTE PHASE PROTEINS WITH SPECIAL REFERENCE TO C-REACTIVE PROTEIN AND RELATED PROTEINS (PENTAXINS) AND SERUM AMYLOID A-PROTEIN
PEPYS, MB
BALTZ, ML
[J]. ADVANCES IN IMMUNOLOGY, 1983, 34 : 141 - 212
[20] INCREASE IN SERUM HAPTOGLOBIN STIMULATED BY PROSTAGLANDINS
SHIM, BS
[J]. NATURE, 1976, 259 (5541) : 326 - 327

← 1 2 3 →