CONCENTRATIONS OF SERUM AMYLOID-A (SAA) AND HAPTOGLOBIN (HP) AS PARAMETERS OF INFLAMMATORY DISEASES IN CATTLE

被引:185
作者
ALSEMGEEST, SPM [1 ]
KALSBEEK, HC [1 ]
WENSING, T [1 ]
KOEMAN, JP [1 ]
VANEDEREN, AM [1 ]
GRUYS, E [1 ]
机构
[1] UNIV UTRECHT, FAC VET MED, DEPT LARGE ANIM MED & NUTR, 3508 TD UTRECHT, NETHERLANDS
关键词
D O I
10.1080/01652176.1994.9694410
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The concentrations of the acute-phase proteins, serum amyloid-A (SAA) and haptoglobin (Hp), were determined in the plasma of healthy cows (n=25) and cows with spontaneous acute (n=6), subacute (n=37), or chronic (n=7) inflammatory diseases. The plasma concentration of SAA alone, Hp alone, and the Hp/SAA ratio, differed significantly (p<0.001) between healthy animals and animals with inflammatory diseases. Plasma Hp concentrations in the group of cows with acute inflammatory diseases were significantly (p<0.01) different from those in the group with chronic inflammatory diseases. Moreover, the Hp/SAA ratio in chronic inflammatory diseases was significantly different from this ratio in acute (p<0.01) and subacute (p<0.05) inflammatory diseases. It is therefore concluded that the plasma concentrations of SAA and Hp and the Hp/SAA ratio are useful parameters to distinguish healthy animals from animals with inflammation and can be helpful in distinguishing between acute and chronic of inflammatory diseases.
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页码:21 / 23
页数:3
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