CONCENTRATIONS OF SERUM AMYLOID-A (SAA) AND HAPTOGLOBIN (HP) AS PARAMETERS OF INFLAMMATORY DISEASES IN CATTLE

被引：185

作者：

ALSEMGEEST, SPM ^{[1
]}

KALSBEEK, HC ^{[1
]}

WENSING, T ^{[1
]}

KOEMAN, JP ^{[1
]}

VANEDEREN, AM ^{[1
]}

GRUYS, E ^{[1
]}

机构：

[1] UNIV UTRECHT, FAC VET MED, DEPT LARGE ANIM MED & NUTR, 3508 TD UTRECHT, NETHERLANDS

来源：

VETERINARY QUARTERLY | 1994年 / 16卷 / 01期

关键词：

D O I：

10.1080/01652176.1994.9694410

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The concentrations of the acute-phase proteins, serum amyloid-A (SAA) and haptoglobin (Hp), were determined in the plasma of healthy cows (n=25) and cows with spontaneous acute (n=6), subacute (n=37), or chronic (n=7) inflammatory diseases. The plasma concentration of SAA alone, Hp alone, and the Hp/SAA ratio, differed significantly (p<0.001) between healthy animals and animals with inflammatory diseases. Plasma Hp concentrations in the group of cows with acute inflammatory diseases were significantly (p<0.01) different from those in the group with chronic inflammatory diseases. Moreover, the Hp/SAA ratio in chronic inflammatory diseases was significantly different from this ratio in acute (p<0.01) and subacute (p<0.05) inflammatory diseases. It is therefore concluded that the plasma concentrations of SAA and Hp and the Hp/SAA ratio are useful parameters to distinguish healthy animals from animals with inflammation and can be helpful in distinguishing between acute and chronic of inflammatory diseases.

引用

页码：21 / 23

页数：3

共 24 条

[1]

ALSEMGEEST SPM, 1993, AM J VET RES, V54, P164

[2]

BAUMANN H, 1989, ANN NY ACAD SCI, V557, P280

[3]

BOOSMAN R, 1989, AM J VET RES, V50, P1690

[4] STUDIES ON HAPTOGLOBIN + HAEMOPLEXIN IN PLASMA OF CATTLE [J].

BREMNER, KC .

AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE, 1964, 42 (06) :643-&

[5]

CHEVILLE NF, 1988, INTRO VET PATHOLOGY, P289

[6] ACUTE PHASE RESPONSE AND MASTITIS IN THE COW [J].

CONNER, JG ;

ECKERSALL, PD ;

DOHERTY, M ;

DOUGLAS, TA .

RESEARCH IN VETERINARY SCIENCE, 1986, 41 (01) :126-128

[7] BOVINE AND CANINE ACUTE PHASE PROTEINS [J].

ECKERSALL, PD ;

CONNER, JG .

VETERINARY RESEARCH COMMUNICATIONS, 1988, 12 (2-3) :169-178

[8] PLASMA HAPTOGLOBIN IN CATTLE (BOS-TAURUS) EXISTS AS POLYMERS IN ASSOCIATION WITH ALBUMIN [J].

ECKERSALL, PD ;

CONNER, JG .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1990, 96 (02) :309-314

[9]

EURELL TE, 1992, CAN J VET RES, V56, P6

[10]

HARVEY J W, 1976, Theriogenology, V6, P133, DOI 10.1016/0093-691X(76)90010-8

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