DOES IRON PLAY A ROLE IN PARKINSONS-DISEASE

被引：14
|
作者：
BAUMINGER, ER
BARCIKOWSKA, M
FRIEDMAN, A
GALAZKAFRIEDMAN, J
HECHEL, D
NOWIK, I
机构：
[1] MED ACAD WARSAW,DEPT NEUROL,WARSAW,POLAND
[2] WARSAW UNIV TECHNOL,INST PHYS,WARSAW,POLAND
来源：
HYPERFINE INTERACTIONS | 1994年 / 91卷 / 1-4期
关键词：
D O I：
10.1007/BF02064618
中图分类号：
O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号：
070203 ; 070304 ; 081704 ; 1406 ;
摘要：
Mossbauer studies of Parkinsonian and control Substantia Nigra (SN) show that the overall amount of iron in SN is about the same in PD and control. At least 90% of this iron is ferritin-like and Fe2+ and/or neuromelanin iron, if present at all, can constitute only less than 10% of the overall iron. During storage in formalin, iron is slowly removed from ferritin and bound to a chelating agent.
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页码：853 / 857
页数：5
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