DOES IRON PLAY A ROLE IN PARKINSONS-DISEASE

被引：14

作者：

BAUMINGER, ER

BARCIKOWSKA, M

FRIEDMAN, A

GALAZKAFRIEDMAN, J

HECHEL, D

NOWIK, I

机构：

[1] MED ACAD WARSAW,DEPT NEUROL,WARSAW,POLAND

[2] WARSAW UNIV TECHNOL,INST PHYS,WARSAW,POLAND

来源：

HYPERFINE INTERACTIONS | 1994年 / 91卷 / 1-4期

关键词：

D O I：

10.1007/BF02064618

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

Mossbauer studies of Parkinsonian and control Substantia Nigra (SN) show that the overall amount of iron in SN is about the same in PD and control. At least 90% of this iron is ferritin-like and Fe2+ and/or neuromelanin iron, if present at all, can constitute only less than 10% of the overall iron. During storage in formalin, iron is slowly removed from ferritin and bound to a chelating agent.

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页码：853 / 857

页数：5

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