IMMUNITY OF CHOLERA IN MAN - RELATIVE ROLE OF ANTIBACTERIAL VERSUS ANTI-TOXIC IMMUNITY

被引：157

作者：

LEVINE, MM

NALIN, DR

CRAIG, JP

HOOVER, D

BERGQUIST, EJ

WATERMAN, D

HOLLEY, HP

HORNICK, RB

PIERCE, NP

LIBONATI, JP

机构：

[1] SUNY,DOWNSTATE MED CTR,BROOKLYN,NY 11203

[2] BALTIMORE CITY HOSP,BALTIMORE,MD 21224

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1979年 / 73卷 / 01期

关键词：

D O I：

10.1016/0035-9203(79)90119-6

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Purified cholera toxoid is antigenic when given enterally and orally. Purified toxoid fails to provide protection against experimental challenge. Clinical cholera confers formidable protection against homologous or heterologous rechallenge. Failure to culture vibrios from intestinal fluid or stool of re-challenge volunteers suggests that the predominant immune mechanism is antibacterial rather than antitoxic. © Royal Society of Tropical Medicine and Hygiene.

引用

页码：3 / 9

页数：7

共 28 条

[1] INFLUENCE OF REPEATED ADMINISTRATION OF ANTIGEN BY ORAL ROUTE ON SPECIFIC ANTIBODY-PRODUCING CELLS IN MOUSE SPLEEN [J].