LEUKINFERON TREATMENT OF ACUTE VIRAL HEPATITIS-B

被引：0

作者：

GOLBAN, TD ^{[1
]}

CHESHIK, SG ^{[1
]}

KUZNETSOV, VP ^{[1
]}

FARBER, NA ^{[1
]}

BELYAEV, DL ^{[1
]}

KIRZHNER, LS ^{[1
]}

BABAYANTS, AA ^{[1
]}

VASINA, VI ^{[1
]}

机构：

[1] NF GAMALEI INST EPIDEMIOL & MICROBIOL,MOSCOW,RUSSIA

来源：

KLINICHESKAYA MEDITSINA | 1994年 / 72卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Leukinferon activity was studied in a controlled trial including 30 patients with acute viral hepatitis. The disease ran a moderate severity course in the majority of the patients. Leukinferon, a combined preparation of natural interferon and cytokines produced by virus-induced leukocytes, has marked immunomodulating properties at moderate antiviral activity. Leukinferon was administered intramuscularly for 10 days according to the following scheme: day 1-1 ampule 3 times, day 2-1 ampule 2 times, day 3-10-1 ampule a day (overall 1 x 10(5)U of interferon). Due to leukinferon the symptoms of intoxication declined, hepatic biochemistry normalized more rapidly as well as the period of viremia and antigenemia. Positive clinical trends correlated with interferon system improvement and activation of natural killers. 6 months later complete recovery was registered in all leukinferon-treated subjects.

引用

页码：27 / 29

页数：3