ON TRIAZOLES .19. THE REACTION OF 5-AMINO-1,2,4-TRIAZOLES WITH FUNCTIONALIZED ACETOACETIC ESTERS [2]

被引：13
|
作者：
REITER, J [1 ]
PONGO, L [1 ]
SOMORAI, T [1 ]
PALLAGI, I [1 ]
机构：
[1] INST DRUG RES,H-1325 BUDAPEST,HUNGARY
来源：
MONATSHEFTE FUR CHEMIE | 1990年 / 121卷 / 2-3期
关键词：
1,2,4-Triazolo[1,5-a]pyrimidinones; 1,2,4-Triazolo[4,3-a]-1,3-diazepinone; !sup]13[!/sup]C-NMR; !sup]1[!/sup]H-NMR; IR-; Novel ring system; UV-;
D O I：
10.1007/BF00809530
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Different "functionalized" alkyl 3-oxo-butyrates (2) were reacted with 5-amino-3-Q-1 H-1,2,4-triazoles (1) to yield 3 and 4 type 1,2,4-triazolo[1,5-a]pyrimidinones. In case of 2 (R1=methyl, R2=1-ethoxycarbonylethyl, R3=ethyl) beside the corresponding derivative 4 the unexpected 5,6-dihydro-6,8-dimethyl-7-ethoxycarbonyl-3-methylthio-1,2,4-triazolo[4,3-a]-1,3-diazepin-5(9 H)-one (7) was isolated, representing a novel ring system. © 1990 Springer-Verlag.
引用
收藏
页码：173 / 187
页数：15
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