A NOVEL PHORBOL ESTER FROM EXCOECARIA-AGALLOCHA

被引：54

作者：

ERICKSON, KL

BEUTLER, JA

CARDELLINA, JH

MCMAHON, JB

NEWMAN, DJ

BOYD, MR

机构：

[1] NCI,FREDERICK CANC RES & DEV CTR,DIV CANC TREATMENT,DEV THERAPEUT PROGRAM,FREDERICK,MD 21702

[2] NCI,FREDERICK CANC RES & DEV CTR,NAT PROD BRANCH,FREDERICK,MD 21702

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1995年 / 58卷 / 05期

关键词：

D O I：

10.1021/np50119a020

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The novel phorbol ester 12-deoxyphorbol 13-(3E,5E-decadienoate) [1] was isolated as the anti-HIV principle of Excoecaria agallocha leaves and stems collected in northwest Australia. The structure was determined by spectral means. Compound 1 was also a potent displacer of [H-3]-phorbol dibutyrate from rat brain membranes.

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页码：769 / 772

页数：4

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