A NOVEL PHORBOL ESTER FROM EXCOECARIA-AGALLOCHA

被引：52
作者：
ERICKSON, KL
BEUTLER, JA
CARDELLINA, JH
MCMAHON, JB
NEWMAN, DJ
BOYD, MR
机构：
[1] NCI,FREDERICK CANC RES & DEV CTR,DIV CANC TREATMENT,DEV THERAPEUT PROGRAM,FREDERICK,MD 21702
[2] NCI,FREDERICK CANC RES & DEV CTR,NAT PROD BRANCH,FREDERICK,MD 21702
来源：
JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1995年 / 58卷 / 05期
关键词：
D O I：
10.1021/np50119a020
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The novel phorbol ester 12-deoxyphorbol 13-(3E,5E-decadienoate) [1] was isolated as the anti-HIV principle of Excoecaria agallocha leaves and stems collected in northwest Australia. The structure was determined by spectral means. Compound 1 was also a potent displacer of [H-3]-phorbol dibutyrate from rat brain membranes.
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页码：769 / 772
页数：4
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