STUDY OF CALCIUM LEVELS IN PATIENTS WITH RENAL FAILURE

Background: Renal failure and its consequences like renal osteodystrophy is a challenge for developing countries like Pakistan. The current study was aimed to evaluate the levels of serum calcium in patients with renal failure so that renal osteodystrophies could be avoided in these patients. Methods: Total ninety subjects of both genders visiting Sheikh Zayed Hospital Lahore were selected randomly. Sixty subjects were clinically diagnosed patients of renal failure. Thirty subjects, clinically normal for kidney functions, were included in the study as control. These were classified in different age/gender based groups. Blood samples from the patients and control were analyzed in an auto-analyzer for serum calcium, serum creatinine and blood urea nitrogen. Results: Serum creatinine and blood urea nitrogen values were statistically significantly higher in the renal failure patients compare to normal subjects. Serum calcium levels were significantly lower in patients with renal failure as compared to normal subjects. Conclusion: It was concluded that positive correlation exists between serum creatinine and blood urea nitrogen. A negative correlation exist between serum creatinine, blood urea nitrogen and serum calcium levels in all group of patients with renal failure.