LONG-TERM ORAL-ADMINISTRATION OF ALUMINUM IN MICE - ALUMINUM DISTRIBUTION IN TISSUES AND EFFECTS ON CALCIUM-METABOLISM

被引：0
作者：
ANGHILERI, LJ
MAINCENT, P
THOUVENOT, P
机构：
[1] UNIV NANCY,FAC PHARM,DEPT BIOPHARM,F-54000 NANCY,FRANCE
[2] UNIV NANCY,MED CTR,NUCL MED SERV,F-54000 NANCY,FRANCE
来源：
ANNALS OF CLINICAL AND LABORATORY SCIENCE | 1994年 / 24卷 / 01期
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D O I：
暂无
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Six months of oral administration of aluminum lactate provokes an important accumulation of aluminum in various tissues of mice. The accumulation magnitude order is spleen > kidney > brain > liver > blood. No systemic toxic effects (weight loss or neurolytic effects) were observed. Values of calcium content and Ca-45-uptake by the different tissues showed no modifications of calcium metabolism. The lack of calcium homeostasis modification caused by a probable aluminum insolubilization, and the incidence of other individual factors on individual deviations from group behavior is discussed.
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页码：22 / 26
页数：5
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