ROLE OF TYPE-1 AND TYPE-2 T-HELPER CELLS IN ALLERGIC DISEASES

被引：70
作者：
KAPSENBERG, ML
JANSEN, HM
BOS, JD
WIERENGA, EA
机构：
[1] UNIV AMSTERDAM, ACAD MED CTR, DEPT PULMONOL, 1105 AZ AMSTERDAM, NETHERLANDS
[2] UNIV AMSTERDAM, ACAD MED CTR, DEPT DERMATOL, 1105 AZ AMSTERDAM, NETHERLANDS
来源：
CURRENT OPINION IN IMMUNOLOGY | 1992年 / 4卷 / 06期
关键词：
D O I：
10.1016/0952-7915(92)90063-K
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Various characteristics of atopic allergic disorders seem to be causally related with the activation of allergen-specific T helper lymphocytes with a type 2 cytokine secretion profile, including high levels of interleukin-4 and interleukin-5. These cytokines are responsible for the occurrence of elevated levels of serum allergen-specific IgE and eosinophilia and play an important role in local inflammatory reactions.
引用
收藏
页码：788 / 793
页数：6
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