HEPATITIS-C VIRUS DOES NOT CAUSE NONALCOHOLIC STEATOHEPATITIS

被引：18
|
作者：
ROGERS, DW
LEE, CH
POUND, DC
KUMAR, S
CUMMINGS, OW
LUMENG, L
机构：
[1] INDIANA UNIV,SCH MED,DEPT MED,975 W WALNUT ST,IB 424,INDIANAPOLIS,IN 46202
[2] INDIANA UNIV,SCH MED,DEPT PATHOL,INDIANAPOLIS,IN 46202
[3] RICHARD L ROUDEBUSH VET ADM MED CTR,INDIANAPOLIS,IN 46202
来源：
DIGESTIVE DISEASES AND SCIENCES | 1992年 / 37卷 / 11期
关键词：
NONALCOHOLIC STEATOHEPATITIS; HEPATITIS-C VIRUS; POLYMERASE CHAIN REACTION; ANTI-C100-3; EIA;
D O I：
10.1007/BF01299852
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The pathogenesis of nonalcoholic steatohepatitis (NASH) remains poorly understood. Since inflammation and fatty changes are associated with hepatitis C (HCV) infection, we have tested the role of HCV in the genesis of NASH. Five consecutive cases of classic NASH were tested by Abbott anti-c100-3 EIA and polymerase chain reaction (PCR) to detect HCV-RNA. All serum specimens were negative for anti-c100-3 (or anti-HCV EIA) and HCV PCR. Based on this study, we conclude that HCV does not play a causative or contributing role in the pathogenesis of NASH.
引用
收藏
页码：1644 / 1647
页数：4
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