HEPATITIS-C VIRUS DOES NOT CAUSE NONALCOHOLIC STEATOHEPATITIS

被引：18

作者：

ROGERS, DW

LEE, CH

POUND, DC

KUMAR, S

CUMMINGS, OW

LUMENG, L

机构：

[1] INDIANA UNIV,SCH MED,DEPT MED,975 W WALNUT ST,IB 424,INDIANAPOLIS,IN 46202

[2] INDIANA UNIV,SCH MED,DEPT PATHOL,INDIANAPOLIS,IN 46202

[3] RICHARD L ROUDEBUSH VET ADM MED CTR,INDIANAPOLIS,IN 46202

来源：

DIGESTIVE DISEASES AND SCIENCES | 1992年 / 37卷 / 11期

关键词：

NONALCOHOLIC STEATOHEPATITIS; HEPATITIS-C VIRUS; POLYMERASE CHAIN REACTION; ANTI-C100-3; EIA;

D O I：

10.1007/BF01299852

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The pathogenesis of nonalcoholic steatohepatitis (NASH) remains poorly understood. Since inflammation and fatty changes are associated with hepatitis C (HCV) infection, we have tested the role of HCV in the genesis of NASH. Five consecutive cases of classic NASH were tested by Abbott anti-c100-3 EIA and polymerase chain reaction (PCR) to detect HCV-RNA. All serum specimens were negative for anti-c100-3 (or anti-HCV EIA) and HCV PCR. Based on this study, we conclude that HCV does not play a causative or contributing role in the pathogenesis of NASH.

引用

页码：1644 / 1647

页数：4

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