DOES INTRAPERITONEAL CA-125 REFLECT DISEASE STATUS

被引：14

作者：

BULLER, RE ^{[1
]}

MANETTA, A ^{[1
]}

BLOSS, JD ^{[1
]}

DISAIA, PJ ^{[1
]}

BERMAN, ML ^{[1
]}

机构：

[1] UNIV CALIF IRVINE,IRVINE MED CTR,DEPT OBSTET & GYNECOL,DIV GYNECOL ONCOL,ORANGE,CA 92668

来源：

GYNECOLOGIC ONCOLOGY | 1991年 / 40卷 / 01期

关键词：

D O I：

10.1016/0090-8258(91)90087-L

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The relationship of serum CA-125 to intraperitoneal (IP) CA-125 was studied in 45 patients with a variety of gynecologic diseases including ovarian carcinoma. In 43 of 45 patients the IP level exceeded the serum level of CA-125. Paracentesis may dramatically alter both levels, thus mimicking surgical debulking. All IP levels of CA-125 measured at second-look coeliotomy for the ovarian cancer patients were within the normal range of IP CA-125 measured at surgery for benign disease. Therefore, intraperitoneal CA-125 is less sensitive than serum CA-125 in predicting intraperitoneal disease status. Likewise it cannot be used to predict the subgroup of ovarian cancer patients with negative second-look coeliotomy who are destined to develop a recurrence of disease. © 1991.

引用

页码：66 / 69

页数：4

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