STIMULATION AND INHIBITION BY PUROMYCIN OF CELL-FREE AMINO ACID INCORPORATION

被引：7

作者：

STENESH, J

SHEN, PY

机构：

[1] Department of Chemistry, Western Michigan University Kalamazoo

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 37卷 / 06期

关键词：

D O I：

10.1016/0006-291X(69)90211-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Puromycin led either to stimulation or to inhibition of phenylalanine incorporation in cell-free systems from Bacillus licheniformis and Bacillus stearothermophilus 10. Stimulation was observed at low puromycin concentrations, at high puromycin concentrations in the presence of excess transfer RNA, and over a narrow range of temperatures. Inhibition was observed at high puromycin concentrations and at temperatures below and above the range where stimulation occurred. Freshly prepared subcellular fractions were inhibited to a greater extent than stored fractions. © 1969.

引用

页码：873 / &

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