STUDIES WITH TSH-131I - DISTRIBUTION IN NORMAL AND HYPOTHYROID RATS

被引：2

作者：

ALTSCHULER, N

PISAREV, MA

MITTA, AEA

ORLANDO, CA

机构：

[1] Atomic Energy Commission, 8250 Buenos Aires, Av. del Libertador

[2] Atomic Energy Commission, Dept. of Chemistry

来源：

INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES | 1968年 / 19卷 / 08期

关键词：

D O I：

10.1016/0020-708X(68)90032-X

中图分类号：

TL [原子能技术]; O571 [原子核物理学];

学科分类号：

0827 ; 082701 ;

摘要：

STUDIES WITH TSH-131I: DISTRIBUTION IN NORMAL AND HYPOTHYROID RATS Radio-iodine labelled TSH was injected into normal and hypothyroid rats. The concentration of the 131I radioactivity was measured at different times in several tissues: liver, kidney, thyroid, pituitary, ovary and Harderian gland. An important localization was observed in the liver and the kidney, mainly in the first minutes after administration. Control studies were performed with Na131I and normal rats and the results obtained indicate that the values observed with TSH-131I are actually due to the localization of the hormone or its metabolites. Physiological mechanisms involved in TSH metabolization are discussed. © 1968.

引用

页码：625 / +

页数：1

共 12 条

[1]

BAKKE JL, 1963, THYROTROPIN, P95

[2] PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY [J].