MODELING THE EFFECTS OF ELECTROSTATIC INTERACTION WITH REACTION-GENERATED PH CHANGE ON THE KINETICS OF IMMOBILIZED ENZYMES

被引：3

作者：

RAMACHANDRAN, KB ^{[1
]}

RATHORE, AS ^{[1
]}

GUPTA, SK ^{[1
]}

机构：

[1] INDIAN INST TECHNOL, DEPT CHEM ENGN, NEW DELHI 110016, INDIA

来源：

CHEMICAL ENGINEERING JOURNAL AND THE BIOCHEMICAL ENGINEERING JOURNAL | 1995年 / 57卷 / 01期

关键词：

D O I：

10.1016/0923-0467(94)06088-6

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

A mathematical model to describe the effects of electrostatic interaction with reaction-generated pH change on the kinetics of immobilized enzyme has been developed to evaluate quantitatively the effect of partitioning of the hydrogen ion in and outside the carrier on overall reaction rate. Numerical results for the overall effectiveness factor were computed for both small and large pore cases. The effects of external mass transfer coefficient and the electrostatic potential on the overall reaction rate were also evaluated. The significance of partitioning coefficient on the proper selection of a carrier for enzyme immobilization is stressed.

引用

页码：B15 / B21

页数：7

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