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LOCALIZATION OF A PORPHYRIN-TYPE COMPOUND IN YEAST PLASMA-MEMBRANES AND ITS INVOLVEMENT IN PHOTOSENSITIZATION OF LIPID-PEROXIDATION
被引：0
作者：
FRAIKIN, GY
STRAKHOVSKAYA, MG
PINYASKINA, EV
机构：
关键词：
PLASMA MEMBRANES;
PORPHYRIN;
SENSITIZER;
LIPID PHOTOPEROXIDATION;
D O I：
暂无
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
Fluorescence of isolated yeast plasma membranes with a peak at 683 nm was recorded and ascribed to a compound absorbing in the visible region of the spectrum. The fluorescence excitation spectrum has a maximum at 410 nm and four less intensive peaks in the range of 500-620 nm, which is characteristic of porphyrins. Visible light (400-600 nm) induces lipid peroxidation in plasma membranes. Intensification of this process when H2O is replaced by D2O and its inhibition by sodium azide are suggestive of the important role of singlet oxygen in initiating photo-induced oxidative reactions. The most probable candidate for the photosensitizer is a membrane-bound porphyrin-type compound.
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页码：877 / 880
页数：4
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