PALLIATIVE, INTRAARTERIAL CHEMOTHERAPY FOR ADVANCED HEAD AND NECK-CANCER USING AN IMPLANTABLE PORT SYSTEM

被引：6

作者：

ECKARDT, A

KELBER, A

机构：

[1] Hannover Medical School, Hannover

来源：

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 1994年 / 52卷 / 12期

关键词：

D O I：

10.1016/0278-2391(94)90044-2

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Purpose: Intraarterial drug therapy for head and neck cancer has been used for more than 30 years. However, because of catheter-related complications occurring quite frequently, this method was abandoned in many institutions. The development of subcutaneously implantable injection ports has renewed interest in regional drug delivery. Patients and Methods: This study reports the authors' experience with 11 injection ports implanted in 10 patients suffering from advanced or recurrent head and neck cancer. Results: The regional chemotherapy was well tolerated; the predominant side effects were hemialopecia and mild unilateral mucositis. Conclusions: These results suggest that regional, intra-arterial chemotherapy using implantable injection ports should be considered for palliative treatment of advanced head and neck cancer.

引用

页码：1243 / 1246

页数：4

共 20 条

[1] INTRAARTERIAL CHEMOTHERAPY FOR HEAD AND NECK-CANCER, .1. THEORETICAL CONSIDERATIONS AND DRUG DELIVERY SYSTEMS [J].

BAKER, SR ;

WHEELER, R .

HEAD & NECK SURGERY, 1983, 6 (02) :664-682

[2] RADIONUCLIDE LOCALIZATION OF INTRAARTERIAL INFUSIONS IN HEAD AND NECK-CANCER [J].

BAKER, SR ;

WHEELER, RH ;

ZIESSMAN, HA ;

MEDVEC, BR ;

THRALL, JH ;

KEYES, JW .

CANCER DRUG DELIVERY, 1984, 1 (02) :145-156

[3]

CHEUNG DK, 1988, CANCER, V61, P903, DOI 10.1002/1097-0142(19880301)61:5<903::AID-CNCR2820610508>3.0.CO

[4]

2-O

[5]

DONEGAN WL, 1976, CANCER, V38, P1479, DOI 10.1002/1097-0142(197610)38:4<1479::AID-CNCR2820380406>3.0.CO

[6]

2-7

[7] INTRAARTERIAL CISPLATIN AND FUDR IN ADVANCED MALIGNANCIES CONFINED TO THE HEAD AND NECK [J].

FORASTIERE, AA ;

BAKER, SR ;

WHEELER, R ;

MEDVEC, BR .

JOURNAL OF CLINICAL ONCOLOGY, 1987, 5 (10) :1601-1606

[8] RESULTS IN 169 PATIENTS WITH CANCER OF HEAD AND NECK TREATED BY INTRA-ARTERIAL INFUSION THERAPY [J].

FRECKMAN, HA .

AMERICAN JOURNAL OF SURGERY, 1972, 124 (04) :501-&

[9] INDUCTION INTRAARTERIAL CISPLATIN AND BLEOMYCIN IN HEAD AND NECK-CANCER [J].

FRUSTACI, S ;

BARZAN, L ;

CARUSO, G ;

GHIRARDO, R ;

FOLADORE, S ;

CARBONE, A ;

COMORETTO, R ;

SERAFINI, I ;

MONFARDINI, S .

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 1991, 13 (04) :291-297

[10]

GALMARINI FC, 1985, AURIS NASUS LARYNX, V12, P234

← 1 2 →