SOS INDUCTION IN ESCHERICHIA-COLI BY SINGLE-STRANDED-DNA OF MUTANT FILAMENTOUS PHAGE - MONITORING BY CLEAVAGE OF LEXA REPRESSOR

被引:21
|
作者
HIGASHITANI, N [1 ]
HIGASHITANI, A [1 ]
HORIUCHI, K [1 ]
机构
[1] NATL INST GENET, DIV MICROBIAL GENET, MISHIMA, SHIZUOKA 411, JAPAN
关键词
D O I
10.1128/jb.177.12.3610-3612.1995
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Infection of Escherichia coli in the presence of chloramphenicol with mutant filamentous phage that are defective in the initiation of minus-strand DNA synthesis induces the SOS response as monitored by cellular LexA levels. This observation demonstrates that single-stranded DNA serves as a primary signal for SOS induction in vivo.
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页码:3610 / 3612
页数:3
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