INTERPRETATION OF THE C-13 NUCLEAR-MAGNETIC-RESONANCE RELAXATION-TIME DATA BY THE COMPUTER-ASSISTED METHOD OF ANALYSIS - APPLICATION TO STRYCHNINE IN SOLUTION

Nuclear magnetic resonance relaxation times of carbons including quaternary ones have been measured for strychnine in CDCl3 at 11.74 T. A computer-assisted method of analysis has been applied to interpret the data based on the three models of molecular reorientational motion. The contribution of dipole-dipole relaxation is estimated for the quaternary carbons in the method of analysis without invoking a separate time-consuming measurement of nuclear Overhauser effect factors; this enables us to discuss the mechanism of relaxation in these carbons. The dipolar part is dominant for the quaternary sp3 carbon, whereas contributions other than the dipolar part are also significant for the quaternary sp2 carbons. © 1990, The Japan Society for Analytical Chemistry. All rights reserved.