Clozapine-induced cataract in a young female

被引:4
作者
Alam, Md. Shahid [1 ]
Kumar, K. V. Praveen [2 ]
机构
[1] Sankara Nethralaya Med Res Fdn, Dept Orbit Oculoplasty Reconstruct & Aesthet Serv, Madras, Tamil Nadu, India
[2] Narayana Med Coll, Dept Ophthalmol, Nellore, Andhra Pradesh, India
关键词
Atypical antipsychotic; cataract; clozapine;
D O I
10.4103/0976-500X.195904
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
A variety of systemic drugs including corticosteroids, amiodarone and antipsychotics have been known to cause cataract formation. Typical antipsychotics such as chlorpromazine have been reported to cause cataract formation in varying rates ranging from 22% to 80%. Cataract as an adverse effect resulting from the long term use of atypical antipsychotic has rarely been mentioned in literature, and there is only a single case report of cataract formation from prolonged use of clozapine. We report a rare case of clozpine induced cataract in a young female. The patient was advised to consult her psychiatrist for a change of drug and to undergo cataract surgery.
引用
收藏
页码:184 / 186
页数:3
相关论文
共 6 条
[1]   Ocular pigmentation associated with clozapine [J].
Borovik, Armand M. ;
Bosch, Martina M. ;
Watson, Stephanie L. .
MEDICAL JOURNAL OF AUSTRALIA, 2009, 190 (04) :210-211
[2]  
Brian G, 2001, B WORLD HEALTH ORGAN, V79, P249
[3]  
DELUISE VP, 1981, ANN OPHTHALMOL, V13, P953
[4]  
GREINER AC, 1964, CAN MED ASSOC J, V90, P663
[5]   Cataract occurrence in patients treated with antipsychotic drugs [J].
Novais e Souza, Valeria Barreto ;
Rodrigues de Moura Filho, Francisco Jose ;
de Matos e Souza, Fabio Gomes ;
Rocha, Camila Farias ;
Mendes Lopes Furtado, Fernando Antonio ;
Almeida Goncalves, Tiago Bessa ;
Ximenes Vasconcelos, Karla Feitosa .
REVISTA BRASILEIRA DE PSIQUIATRIA, 2008, 30 (03) :222-226
[6]  
Yanoff M, 2004, OPHTHALMOLOGY, P381