IMMUNOCYTOCHEMICAL EVIDENCE FOR A MITOCHONDRIALLY LOCATED NITRIC-OXIDE SYNTHASE IN BRAIN AND LIVER

被引：171

作者：

BATES, TE ^{[1
]}

LOESCH, A ^{[1
]}

BURNSTOCK, G ^{[1
]}

CLARK, JB ^{[1
]}

机构：

[1] UNIV LONDON UNIV COLL,DEPT ANAT & DEV BIOL,LONDON WC1E 6BT,ENGLAND

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 213卷 / 03期

关键词：

D O I：

10.1006/bbrc.1995.2213

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in non-synaptosomal rat brain mitochondria and rat liver mitochondria, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that nitric oxide synthase located in mitochondria is involved in the regulation of mitochondrial oxidative phosphorylation is discussed, (C) 1995 Academic Press, Inc.

引用

页码：896 / 900

页数：5

共 24 条

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